Monoclonal Antibodies

Monoclonal antibodies (mAbs) developed by AffiNEURO are highly specific tools used for the detection, quantification, and manipulation of neurobiological targets. These antibodies are produced from a single clone of B cells, ensuring homogeneity and specificity toward a single epitope on the target antigen.

Content and Characteristics:

  • Production:
    • Hybridoma Technology: Monoclonal antibodies are generated using hybridoma technology, where a single B cell is fused with a myeloma cell, resulting in a hybrid cell line capable of continuous antibody production.
    • Recombinant Technology: Advanced mAbs are produced using recombinant DNA methods to enhance purity, reproducibility, and customization.
  • Specificity and Affinity:
    • High specificity for neural targets, such as neurotransmitters, receptors, neurotrophic factors, or disease-associated proteins.
    • Superior binding affinity ensures reliable and consistent results.
  • Formats:
    • Available as unlabeled antibodies or conjugated with fluorescent dyes, enzymes (e.g., HRP, AP), or biotin for diverse applications.
    • Multiple isotypes, such as IgG1, IgG2a, and IgM, tailored for specific experimental needs.

Applications:

  • Neuroscience Research:
    • Biomarker Detection: Detect and quantify biomarkers associated with neurological development, synaptic function, or neurodegeneration (e.g., amyloid-β, tau proteins).
    • Pathway Studies: Investigate signaling pathways and molecular interactions in neuronal cells.
  • Disease Modeling:
    • Neurodegenerative Disorders: Study pathophysiological mechanisms in diseases like Alzheimer’s, Parkinson’s, and Huntington’s.
    • Neuroinflammatory Conditions: Analyze markers of inflammation in the central nervous system (e.g., microglial activation).
  • Drug Development:
    • Validate therapeutic targets and assess drug efficacy in preclinical studies.
    • Monitor pharmacodynamic and pharmacokinetic profiles of therapeutic agents.

For detailed product specifications, datasheets, and ordering information, consult AffiNEURO's official resources or technical support team.

445.00 445.0 USD
AffiNEURO® Serotonin monoclonal Antibody
CAT# AFG-SML-037
Size: 50 µL
445.00 445.0 USD
445.00 445.0 USD
445.00 445.0 USD
445.00 445.0 USD
445.00 445.0 USD
445.00 445.0 USD
445.00 445.0 USD
AffiNEURO® GABA mouse monoclonal Antibody
CAT# AFG-SML-010
Size: 50 µL
445.00 445.0 USD
445.00 445.0 USD
445.00 445.0 USD
445.00 445.0 USD